CD207 (Langerin) antibodies, mouse

CD207 (Langerin) antibodies, mouse

Clone: caa8-28H10 | Dilution: 1:10
CD207, also known as Langerin is a 48kDa transmembrane type II C-type lectin containing a single carbohydrate recognition domain in its extracellular region. Langerin is specifically expressed on epidermal Langerhans cells and dermal CD103
+
dendritic cells. It displays Ca
2+
-dependent binding specificity for mannose, N-acetyl-glucosamine, and fucose and is involved in antigen recognition, uptake and transport to the Birbeck granules, whose formation is dependent on Langerin expression. The CD207 epitope shows trypsin as well as collagenase sensitivity.

Alternative names

Langerin

Technical specifications

  • Antigen: CD207 (Langerin)
  • Clone: caa8-28H10
  • Isotype: rat IgG2a
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: Langerin
  • Entrez Gene ID: 246278
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: dendritic cells, Langerhans cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, PE-Vio770, Biotin, FITC
Product options: 6
30 µg in 1 mL (1)
EUR 40,00 
30 µg in 1 mL (1)
EUR 80,00 
30 µg in 1 mL (1)
EUR 80,00 
30 µg in 1 mL (1)
EUR 95,00 
30 µg in 1 mL (1)
EUR 100,00 
30 µg in 1 mL (1)
EUR 40,00 

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