CD2 antibodies, human

CD2 antibodies, human

Clone: REA972 | Dilution: 1:50
Clone REA972 recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. CD2 functions as a co-stimulatory molecule on T and NK cells and is a receptor for other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58). It belongs to the Ig superfamily and is involved in cell signaling and lymphocyte adhesion. The CD2 antibody reacts with 80–90 % of peripheral blood lymphocytes and more than 95% of thymocytes and recognizes all T cells and a subset of NK cells.
Additional information: Clone REA972 displays negligible binding to Fc receptors.

Alternative Names

LFA-2, SRBC-R, T11, SRBC

Technical specifications

  • Antigen: CD2
  • Clone: REA972
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LFA-2, SRBC-R, T11, SRBC
  • Entrez Gene ID: 914
  • Molecular mass of antigen [kDa]: 37
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: B cells, lymphocytes, macrophages, mast cells, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770
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