CD192 (CCR2) antibodies, human

CD192 (CCR2) antibodies, human

Clone: REA264
Clone REA264 recognizes the CD192 antigen, a G-protein–linked seven transmembrane receptor which is also known as C-C chemokine receptor type 2 (CCR2) or monocyte chemoattractant protein 1 receptor (MCP-1-R). Two spliced variants of CD192 (CD192A and CD192B) are expressed on peripheral monocytes and basophils as a result of alternate splicing of a single gene and differ at the C-terminal end. CD192 and its main ligand CCL2 have been implicated in a wide range of immunobiological processes and neuropathologies, including recruitment of monocytes and regulation of bone marrow homeostasis, as well as multiple sclerosis, HIV-associated dementia, Alzheimer’s disease, and neuropathic pain.
Additional information: Clone REA264 displays negligible binding to Fc receptors.

Alternative names

CCR2, CC-CKR-2, CCR-2A, CCR2B, Ckr2, CKR2A, Ckr2b, Cmkbr2, MCP-1-R

Technical specifications

  • Antigen: CD192 (CCR2)
  • Clone: REA264
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CCR2, CC-CKR-2, CCR-2A, CCR2B, Ckr2, CKR2A, Ckr2b, Cmkbr2, MCP-1-R
  • Entrez Gene ID: 1231
  • Molecular mass of antigen [kDa]: 42
  • Distribution of antigen: basophils, monocytes
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL
EUR 195,00