CD19 antibodies, human

CD19 antibodies, human

Clone: REA675 | Dilution: 1:11
REA675 recognizes the human CD19 antigen, a type I transmembrane glycoprotein of 95 kDa that belongs to the immunglobulin superfamily. CD19 is expressed on B cells throughout most stages of B cell differentiation, though its expression is down-regulated during their terminal differentiation to plasma cells. Expression of CD19 is also found in the majority of B cell–derived malignancies. CD19 is further present on follicular dendritic cells. On B cells, CD19 associates with CD21, CD81, and CD225 (Leu-13) forming a signal transduction complex.
Additional information: Clone REA675 displays negligible binding to Fc receptors.

Alternative Names

B4, Leu-12

Technical specifications

  • Antigen: CD19
  • Clone: REA675
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: B4, Leu-12
  • Distribution of antigen: B cells, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, VioGreen
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA675
SJ25C1++
HIB19++
LT19++
J3-119++
Product options: 5

Product information

Size
Order no.
Price

CD19-FITC, human

  • REA675
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-349
EUR 86,00 

CD19-FITC, human

  • REA675
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-248
EUR 252,00 

CD19-APC, human

  • REA675
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-351
EUR 146,00 

CD19-VioGreen, human

  • REA675
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-355
EUR 146,00 

CD19-VioGreen, human

  • REA675
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-254
EUR 322,00 

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