CD177 antibodies, human

CD177 antibodies, human

Clone: REA258 | Dilution: 1:11
Clone REA258 recognizes CD177, which is also known as neutrophil specific antigen 1. CD177, a member of the µPAR family, is a 58–64 kDa glycosylphosphatidylinositol-anchored glycoprotein expressed exclusively by subset of neutrophils, neutrophilic metamyelocytes, and myelocytes and is suggested to play a role in neutrophil mediated immune reponse as evident by its up-regulation on neutrophils in a number of inflammatory settings such as bacterial infection. Furthermore, CD177 can directly bind to PECAM-1 allowing neutrophil-endothelial cell interactions and thus contributing to neutrophil transmigration. Overexpression of CD177 is also seen in patients with polycythemia vera, making it a useful diagnostic marker.
Additional information: Clone REA258 displays negligible binding to Fc receptors.

Alternative Names

HNA-2a, NB1, NB1 GP, PRV-1, PRV1

Technical specifications

  • Antigen: CD177
  • Clone: REA258
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HNA-2a, NB1, NB1 GP, PRV-1, PRV1
  • Entrez Gene ID: 57126
  • Molecular mass of antigen [kDa]: 41
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD177-FITC, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-521
EUR 74,00 

CD177-FITC, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-518
EUR 185,00 

CD177-PE, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-525
EUR 91,00 

CD177-PE, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-523
EUR 236,00 

CD177-APC, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-512
EUR 113,00 

CD177-APC, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-511
EUR 255,00 

CD177-PE-Vio770, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-528
EUR 113,00 

CD177-PE-Vio770, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-527
EUR 278,00 

CD177-APC-Vio770, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-517
EUR 101,00 

CD177-APC-Vio770, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-514
EUR 278,00 

CD177-Biotin, human

  • REA258
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-530
EUR 74,00 

CD177-Biotin, human

  • REA258
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-529
EUR 236,00 

Related products

3 products available