CD172g (SIRPγ) antibodies, human

CD172g (SIRPγ) antibodies, human

Clone: REA479 | Dilution: 1:11
Clone REA479 recognizes the human CD172g antigen, a single-pass type I membrane protein also known as signal-regulatory protein γ (SIRPγ) or signal-regulatory protein β 2 (SIRPβ2). Signal regulatory proteins (SIRPs) are a family of transmembrane receptor-like signaling proteins that are abundantly expressed in hematopoietic cells, including granulocytes, monocytes, dendritic cells, and lymphocytes. In addition, SIRPs are expressed in neuronal cells and certain types of cancer cells. CD172g is the only member of the SIRP family that is expressed on T cells, some B cells, CD56
bright
natural killer (NK) cells, and all activated NK cells. CD172g does bind CD47, albeit with less affinity than CD172a (SIRPα). This interaction mediates cell-cell adhesion, rather than inhibitory signals. The adhesion mediated by contact of CD172g on T cells with CD47 on antigen-presenting cells (APCs) promotes antigen-specific T cell proliferation and costimulates T cell activation.
Additional information: Clone REA479 displays negligible binding to Fc receptors.

Alternative Names

SIRPG, SIRP-g, SIRPB2, SIRPgamma

Technical specifications

  • Antigen: CD172g (SIRPγ)
  • Clone: REA479
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SIRPG, SIRP-g, SIRPB2, SIRPgamma
  • Entrez Gene ID: 55423
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: B cells, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD172g (SIRPγ)-VioBright FITC, human

  • REA479
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-155
EUR 154,00 

CD172g (SIRPγ)-VioBright FITC, human

  • REA479
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-100
EUR 308,00 

CD172g (SIRPγ)-PE, human

  • REA479
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-152
EUR 112,00 

CD172g (SIRPγ)-PE, human

  • REA479
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-097
EUR 296,00 

CD172g (SIRPγ)-APC, human

  • REA479
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-153
EUR 146,00 

CD172g (SIRPγ)-APC, human

  • REA479
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-098
EUR 322,00 

CD172g (SIRPγ)-Biotin, human

  • REA479
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-151
EUR 86,00 

CD172g (SIRPγ)-Biotin, human

  • REA479
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-096
EUR 252,00 

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