CD172a (SIRPα) antibodies, human

CD172a (SIRPα) antibodies, human

Clone: REA144 | Dilution: 1:11
Clone REA144 recognizes CD172a, which is also known as signal regulatory protein α (SIRPα). CD172a belongs to the Ig superfamily and is 75–110 kDa, single-pass type I regulatory membrane protein. Expression of CD172a is found primarily on hematopoietic stem cells, neurons, and myeloid cells such as macrophages, monocytes, dendritic cells, granulocytes, and myeloid progenitors. CD172a phosphorylated at intracellular tyrosine sites, in response to extracellular stimuli, serves as the docking site for phosphatases such as SHP-1, SHP-2, or SHIP, which inturn desphosphorylate molecules involved in regulating various physiological effects. CD47 has been suggested as a ligand of CD172a.
Additional information: Clone REA144 displays negligible binding to Fc receptors.

Alternative Names

SIRPα, Bit, Mfr, MYD-1, P84, Ptpns1, SHPS-1, Sirp

Technical specifications

  • Antigen: CD172a (SIRPα)
  • Clone: REA144
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SIRPα, Bit, Mfr, MYD-1, P84, Ptpns1, SHPS-1, Sirp
  • Entrez Gene ID: 140885
  • Molecular mass of antigen [kDa]: 52
  • Distribution of antigen: macrophages, dendritic cells, myeloid cells, monocytes, hematopoietic stem cells, neurons
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD172a (SIRPα)-FITC, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-897
EUR 74,00 

CD172a (SIRPα)-FITC, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-896
EUR 185,00 

CD172a (SIRPα)-PE, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-783
EUR 91,00 

CD172a (SIRPα)-PE, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-781
EUR 236,00 

CD172a (SIRPα)-APC, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-785
EUR 113,00 

CD172a (SIRPα)-APC, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-784
EUR 255,00 

CD172a (SIRPα)-PE-Vio770, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-793
EUR 113,00 

CD172a (SIRPα)-PE-Vio770, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-840
EUR 278,00 

CD172a (SIRPα)-APC-Vio770, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-790
EUR 101,00 

CD172a (SIRPα)-APC-Vio770, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-787
EUR 278,00 

CD172a (SIRPα)-Biotin, human

  • REA144
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-769
EUR 74,00 

CD172a (SIRPα)-Biotin, human

  • REA144
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-768
EUR 236,00 

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