CD171 (L1CAM) antibodies, mouse

CD171 (L1CAM) antibodies, mouse

Clone: 555 | Dilution: 1:10
The monoclonal antibody clone 555 recognizes CD171, a single pass type I membrane glycoprotein belonging to the immunoglobulin superfamily. Also known as L1CAM (L1 cell adhesion molecule) or NCAM-L1, CD171 belongs to a subgroup of cell adhesion molecules, which consists of six Ig-like domains, five fibronectin type III (FNIII)-like domains, a transmembrane region and a cytoplasmic domain. Expression of CD171 is found on tetanus-toxin positive neurons1, endothelial cells, certain epithelial cells, reticular fibroblasts and several malignant tumors including colon and breast carcinomas, colon melanoma, tumor cells of neuronal and mesothelial origin, where a role of CD171 in augmenting tumor growth has been demonstrated. Thus, CD171 is considered a novel marker for carcinoma progression.
CD171 displays binding to a number of ligands including homophilic interaction with itself and heterophilic binding to integrins, other cell adhesion molecules, extracellular matrix molecules and thus plays a vital role in cell adhesion and signal transduction. It is involved in the development of the nervous system and regulates processes such as neuron–neuron adhesion, myelination, axonal guidance, and neuronal migration.

Alternative Names

L1CAM, L1, NCAM-L1

Technical specifications

  • Antigen: CD171 (L1CAM)
  • Clone: 555
  • Isotype: rat IgG2a
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: L1CAM, L1, NCAM-L1
  • Entrez Gene ID: 16728
  • Molecular mass of antigen [kDa]: 139
  • Distribution of antigen: endothelial cells, fibroblasts, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin, pure
Product options: 11

Product information

Size
Order no.
Price

CD171 (L1CAM)-VioBright FITC, mouse

  • 555
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-106-156
EUR 48,00 

CD171 (L1CAM)-VioBright FITC, mouse

  • 555
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-106-105
EUR 64,00 

CD171 (L1CAM)-PE, mouse

  • 555
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-865
EUR 27,00 

CD171 (L1CAM)-PE, mouse

  • 555
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-243
EUR 54,00 

CD171 (L1CAM)-APC, mouse

  • 555
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-864
EUR 44,00 

CD171 (L1CAM)-APC, mouse

  • 555
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-221
EUR 86,00 

CD171 (L1CAM)-PE-Vio770, mouse

  • 555
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-870
EUR 44,00 

CD171 (L1CAM)-PE-Vio770, mouse

  • 555
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-135
EUR 86,00 

CD171 (L1CAM)-Biotin, mouse

  • 555
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-004
EUR 15,00 

CD171 (L1CAM)-Biotin, mouse

  • 555
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-856
EUR 32,00 

CD171 (L1CAM) pure, mouse

  • 555
  • For research use only
100 µg in 1 mL
130-115-812
EUR 507,00 

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