CD16b antibodies, human

CD16b antibodies, human

Clone: REA589 | Dilution: 1:11
Clone REA589 recognizes the human CD16b antigen, a glycosylphosphatidylinositol-anchored protein known as low affinity immunoglobulin gamma Fc region receptor III-B. CD16 is expressed in two different isoforms, FcγRIIIa (CD16a) and FcγRIIIb (CD16b) Fc receptors, that bind to the Fc portion of IgG antibodies which mediates NK cell activating. CD16b is present on polymorphonuclear leukocytes (neutrophils), whereas the transmembrane form CD16a is found on human NK cells, macrophages, and mast cells.
Additional information: Clone REA589 displays negligible binding to Fc receptors.

Alternative Names

FCGR3B, Fc-gamma RIIIb, FCG3, FCGR3, FcR-10, FcRIII, FcRIIIb

Technical specifications

  • Antigen: CD16b
  • Clone: REA589
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FCGR3B, Fc-gamma RIIIb, FCG3, FCGR3, FcR-10, FcRIII, FcRIIIb
  • Entrez Gene ID: 2215
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: leukocytes, NK cells, macrophages, mast cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, APC-Vio770, Biotin
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