CD158i (KIR2DS4) antibodies, human

CD158i (KIR2DS4) antibodies, human

Clone: REA860 | Dilution: 1:50
Clone REA860 recognizes the human CD158i antigen, also known as KIR2DS4, a member of the killer immunoglobulin-like receptor (KIR) family expressed on natural killer (NK) cells and some T cells. CD158i (KIR2DS4) provides an activation signal for NK lytic activity upon interaction with its ligand, HLA-Cw4, in an antigen-independent manner. KIRs are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. The receptor family can be subdivided functionally according to the length of their cytoplasmic tail in inhibitory and activating KIRs.
Additional information: Clone REA860 displays negligible binding to Fc receptors.

Alternative names

KIR2DS4

Technical specifications

  • Antigen: CD158i (KIR2DS4)
  • Clone: REA860
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DS4
  • Entrez Gene ID: 3809
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196
    2. Djeu, J. et al. (2002) A view to a kill: signals triggering cytotoxicity. Clin. Cancer Res. 8: 636-640
    3. Kratz, G. et al. (2004) MHC Class I-independent recognition of NK-activating receptor KIR2DS4. J. Immunol. 173: 1819-1825
Product options: 20
130-114-771

CD158i (KIR2DS4)-FITC, human

for 30
tests
(1)
EUR 90,00 
130-114-614

CD158i (KIR2DS4)-FITC, human

for 100
tests
(1)
EUR 220,00 
130-114-772

CD158i (KIR2DS4)-PE, human

for 30
tests
(1)
EUR 110,00 
130-114-615

CD158i (KIR2DS4)-PE, human

for 100
tests
(1)
EUR 265,00 
130-114-773

CD158i (KIR2DS4)-APC, human

for 30
tests
(1)
EUR 110,00 
130-114-616

CD158i (KIR2DS4)-APC, human

for 100
tests
(1)
EUR 265,00 
130-114-779

CD158i (KIR2DS4)-VioBlue, human

for 30
tests
(1)
EUR 115,00 
130-114-622

CD158i (KIR2DS4)-VioBlue, human

for 100
tests
(1)
EUR 275,00 
130-114-780

CD158i (KIR2DS4)-PE-Vio615, human

for 30
tests
(1)
EUR 120,00 
130-114-623

CD158i (KIR2DS4)-PE-Vio615, human

for 100
tests
(1)
EUR 290,00 
130-114-774

CD158i (KIR2DS4)-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-114-617

CD158i (KIR2DS4)-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-114-775

CD158i (KIR2DS4)-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-114-618

CD158i (KIR2DS4)-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-114-776

CD158i (KIR2DS4)-PerCP-Vio700, human

for 30
tests
(1)
EUR 120,00 
130-114-619

CD158i (KIR2DS4)-PerCP-Vio700, human

for 100
tests
(1)
EUR 290,00 
130-114-777

CD158i (KIR2DS4)-VioBright 515, human

for 30
tests
(1)
EUR 150,00 
130-114-620

CD158i (KIR2DS4)-VioBright 515, human

for 100
tests
(1)
EUR 360,00 
130-114-770

CD158i (KIR2DS4)-Biotin, human

for 30
tests
(1)
EUR 90,00 
130-114-613

CD158i (KIR2DS4)-Biotin, human

for 100
tests
(1)
EUR 220,00