CD157 (BST-1) antibodies, human

CD157 (BST-1) antibodies, human

Clone: REA465 | Dilution: 1:11
Clone REA465 recognizes the human CD157 antigen, a glycosylphosphatidylinositol (GPI) linked protein, which is also known as bone marrow stromal antigen 1 (BST-1) or cyclic ADP-ribose hydrolase 2. CD157, a member of the CD38 gene family, is an NAD-metabolizing ectoenzyme and a signaling molecule, which synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, former a second messenger that elicits calcium release from intracellular stores. It is mainly expressed by cells of the myeloid lineage, bone marrow stroma, and vascular endothelium. CD157 is also expressed by ovarian cancer epithelium and by peritoneal mesothelial cells, where it is implicated in tumor dissemination. Further, it is endowed with receptor-like features observed in different cell types and transduces signals by interacting with transmembrane partner molecules, a strategy shared by other GPI-anchored molecules. CD157 is involved in neutrophil polarization, adhesion, and motility and controls transendothelial migration.
Additional information: Clone REA465 displays negligible binding to Fc receptors.

Alternative Names

BST-1

Technical specifications

  • Antigen: CD157 (BST-1)
  • Clone: REA465
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: BST-1
  • Entrez Gene ID: 683
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: endothelial cells, granulocytes, bone marrow, stromal cells, macrophages, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD157 (BST-1)-VioBright FITC, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-985
EUR 154,00 

CD157 (BST-1)-VioBright FITC, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-921
EUR 308,00 

CD157 (BST-1)-PE, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-981
EUR 112,00 

CD157 (BST-1)-PE, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-917
EUR 296,00 

CD157 (BST-1)-APC, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-982
EUR 146,00 

CD157 (BST-1)-APC, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-918
EUR 322,00 

CD157 (BST-1)-PE-Vio770, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-983
EUR 146,00 

CD157 (BST-1)-PE-Vio770, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-919
EUR 322,00 

CD157 (BST-1)-APC-Vio770, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-984
EUR 129,00 

CD157 (BST-1)-APC-Vio770, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-920
EUR 308,00 

CD157 (BST-1)-Biotin, human

  • REA465
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-980
EUR 86,00 

CD157 (BST-1)-Biotin, human

  • REA465
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-916
EUR 252,00 

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