CD137 antibodies – functional grade, mouse

CD137 antibodies – functional grade, mouse

Clone: 17B5-1H1
Clone 17B5 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8
+
T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in
in vitro
functional assays.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Technical specifications

  • Antigen: CD137
  • Clone: 17B5-1H1
  • Isotype: hamster IgG2
  • Alternative names of antigen: TNFRSF9, 4-1BB, CDw137, ILA, Ly63
  • Entrez Gene ID: 21942
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, fibroblasts, lymphocytes, macrophages, monocytes, T cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD137 pure - functional grade, mouse

  • 17B5-1H1
  • For research use only
500 µg in 0.5 mL
130-097-139
EUR 330,00