CD132 antibodies, human

CD132 antibodies, human

Clone: REA313 | Dilution: 1:11
Clone REA313 recognizes the human CD132 antigen, a 65–70 kDa single-pass type I membrane protein also known as common γ chain, which is shared by the IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 receptors. CD132 is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. The most common form of severe combined immune deficiency in humans, with lack of circulating T cells, a normal or increased number of B lymphocytes, and an X-linked pattern of inheritance (XSCID) has been shown to be due to defects of the CD132 gene.
Additional information: Clone REA313 displays negligible binding to Fc receptors.

Alternative Names

IL2RG, CIDX, IL-2RG, IMD4, p64, SCIDX, SCIDX1

Technical specifications

  • Antigen: CD132
  • Clone: REA313
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: IL2RG, CIDX, IL-2RG, IMD4, p64, SCIDX, SCIDX1
  • Entrez Gene ID: 3561
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: T cells, B cells, lymphocytes, NK cells, monocytes, granulocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected References

    1. Ramsey, C. et al. (2008) The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J. Immunol. 180(8): 5320-5326
    2. Russell, S. M. et al. (1993) Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science 262(5141): 1880-1883
    3. Takesita, T. et al. (1992) Cloning of the gamma chain of the human IL-2 receptor. Science 257(5068): 379-382
Product options: 8

Product information

Size
Order no.
Price

CD132-PE, human

  • REA313
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-659
EUR 110,00 

CD132-PE, human

  • REA313
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-587
EUR 265,00 

CD132-APC, human

  • REA313
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-660
EUR 110,00 

CD132-APC, human

  • REA313
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-588
EUR 265,00 

CD132-PE-Vio770, human

  • REA313
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-661
EUR 120,00 

CD132-PE-Vio770, human

  • REA313
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-589
EUR 290,00 

CD132-Biotin, human

  • REA313
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-070
EUR 90,00 

CD132-Biotin, human

  • REA313
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-044
EUR 220,00