CD126 (IL-6Rα) antibodies, mouse and rat

CD126 (IL-6Rα) antibodies, mouse and rat

Clone: REA620 | Dilution: 1:10
Clone REA620 recognizes the mouse CD126 antigen, a type I cytokine receptor, also known as interleukin 6 receptor subunit alpha (IL-6Rα) or membrane glycoprotein 80 (gp80). CD126 is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. It associates with the IL-6 receptor β chain (CD130 or gp130) resulting in the formation of a functional high affinity IL-6 receptor complex. IL-6 plays essential roles in immune response, acute phase reaction, and hematopoiesis. It is an essential factor for B cell differentiation to antibody-forming cells. Deregulated expression of the IL-6 gene is involved in polyclonal plasma cell abnormalities and oncogenesis of plasma cell neoplasias. IL-6 functions as a potent growth factor for multiple myelomas as well as plasmacytomas.
Additional information: Clone REA620 displays negligible binding to Fc receptors.

Alternative Names

IL-6R 1, IL-6R-alpha, IL-6RA, IL-6R, Il6r

Technical specifications

  • Antigen: CD126 (IL-6Rα)
  • Clone: REA620
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: IL-6R 1, IL-6R-alpha, IL-6RA, IL-6R, Il6r
  • Entrez Gene ID: 16194
  • Molecular mass of antigen [kDa]: 49
  • Distribution of antigen: B cells, monocytes, T cells, plasma cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD126 (IL-6Rα)-PE, mouse and rat

  • REA620
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-625
EUR 39,00 

CD126 (IL-6Rα)-PE, mouse and rat

  • REA620
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-566
EUR 57,00 

CD126 (IL-6Rα)-APC, mouse and rat

  • REA620
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-626
EUR 55,00 

CD126 (IL-6Rα)-APC, mouse and rat

  • REA620
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-567
EUR 83,00 

CD126 (IL-6Rα)-PE-Vio770, mouse and rat

  • REA620
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-627
EUR 67,00 

CD126 (IL-6Rα)-PE-Vio770, mouse and rat

  • REA620
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-568
EUR 101,00 

CD126 (IL-6Rα)-Biotin, mouse and rat

  • REA620
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-109-624
EUR 20,00 

CD126 (IL-6Rα)-Biotin, mouse and rat

  • REA620
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-109-565
EUR 32,00 

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