CD11b antibodies, mouse

CD11b antibodies, mouse

Clone: REA592 | Dilution: 1:50
Clone REA592 recognizes the mouse CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. CD11b is expressed on monocytes, macrophages, and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5
+
B-1 cells, and subsets of dendritic cells. Clone REA592 recognizes also the non-human primate and human CD11b antigen.
Additional information: Clone REA592 displays negligible binding to Fc receptors.

Alternative Names

integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Technical specifications

  • Antigen: CD11b
  • Clone: REA592
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: integrin αM, Mac-1 α, Integrin alpha-M, CR3A
  • Entrez Gene ID: 3684, 16409
  • Molecular mass of antigen [kDa]: 126
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    , human
  • Distribution of antigen: monocytes, macrophages, microglia
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, PerCP-Vio700, Biotin
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA592
M1/70++
ICRF44-
CBRM1/5-
REA713-
Product options: 13

Product information

Size
Order no.
Price

CD11b-VioBright FITC, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-805
EUR 86,00 

CD11b-VioBright FITC, mouse

  • REA592
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-113-243
EUR 233,00 

CD11b-PE, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-806
EUR 59,00 

CD11b-APC, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-802
EUR 112,00 

CD11b-VioBlue, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-810
EUR 118,00 

CD11b-VioGreen, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-811
EUR 162,00 

CD11b-PE-Vio615, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-807
EUR 138,00 

CD11b-PE-Vio615, mouse

  • REA592
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-113-245
EUR 294,00 

CD11b-PE-Vio770, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-808
EUR 100,00 

CD11b-PE-Vio770, mouse

  • REA592
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-113-246
EUR 280,00 

CD11b-PerCP-Vio700, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-809
EUR 100,00 

CD11b-Biotin, mouse

  • REA592
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-804
EUR 40,00 

CD11b-Biotin, mouse

  • REA592
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-113-242
EUR 135,00 

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