CD11a antibodies, human

CD11a antibodies, human

Clone: REA378 | Dilution: 1:11
Clone REA378 recognizes the human CD11a antigen, a single-pass type I membrane protein also known as integrin α-L (ITGAL). Integrins are heterodimeric adhesion molecules comprised of α- and β-subunits that participate in immune cell interactions as well as in immune cell-extracellular matrix interactions. CD11a combines with CD18 (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 is a receptor for CD54 (ICAM-1), CD102 (ICAM-2), CD50 (ICAM-3), and CD242 (ICAM-4). It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T cell–mediated killing, and antibody dependent killing by granulocytes and monocytes. Interactions between LFA-1 and CD54 (ICAM-1) play a critical role in T cell–B cell collaboration.
Additional information: Clone REA378 displays negligible binding to Fc receptors.

Alternative Names

ITGAL, LFA-1, LFA1A, Leukocyte function-associated molecule 1 α chain

Technical specifications

  • Antigen: CD11a
  • Clone: REA378
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGAL, LFA-1, LFA1A, Leukocyte function-associated molecule 1 α chain
  • Entrez Gene ID: 3683
  • Molecular mass of antigen [kDa]: 126
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
    , capuchin monkey, horse, cattle (bovine, cow), sheep, dog, rabbit
  • Distribution of antigen: leukocytes, T cells, granulocytes, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
Product options: 16

Product information

Size
Order no.
Price

CD11a-FITC, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-478
EUR 65,00 

CD11a-FITC, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-435
EUR 255,00 

CD11a-PE, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-479
EUR 85,00 

CD11a-PE, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-436
EUR 300,00 

CD11a-APC, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-480
EUR 111,00 

CD11a-APC, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-437
EUR 326,00 

CD11a-VioBlue, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-477
EUR 85,00 

CD11a-VioBlue, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-434
EUR 300,00 

CD11a-PE-Vio770, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-481
EUR 111,00 

CD11a-PE-Vio770, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-438
EUR 326,00 

CD11a-APC-Vio770, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-482
EUR 98,00 

CD11a-APC-Vio770, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-439
EUR 313,00 

CD11a-PerCP-Vio700, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-483
EUR 98,00 

CD11a-PerCP-Vio700, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-440
EUR 313,00 

CD11a-Biotin, human

  • REA378
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-476
EUR 65,00 

CD11a-Biotin, human

  • REA378
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-433
EUR 255,00 

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