CD107b antibodies, human

CD107b antibodies, human

Clone: H4B4 | Dilution: 1:10
The monoclonal antibody H4B4 reacts with human CD107b, also known as lysosomal-associated membrane protein-2 (LAMP-2), which is a 120 kDa highly glycosylated type I transmembrane protein. It is widely located in lysosomal/endosomal membranes in a high variety of cell types and also expressed on degranulating T cells, activated platelets, and some tumor cell lines. CD107b is involved in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation as well as in tumor cell metastasis.

Alternative names

LAMP-2, LAMPB, LGP110

Technical specifications

  • Antigen: CD107b
  • Clone: H4B4
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: LAMP-2, LAMPB, LGP110
  • Entrez Gene ID: 3920
  • Molecular mass of antigen [kDa]: 42
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: leukocytes, platelets, T cells, lymphocytes, tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Grutzkau, A. et al. (2004) LAMP-1 and LAMP-2, but not LAMP-3, are reliable markers for activation-induced secretion of human mast cells. Cytometry A 61(1): 62-68
    2. Carlsson, S. R. et al. (1988) Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J. Biol. Chem. 263: 18911-18919
    3. Betts, M. R. et al. (2004) Detection of T-cell degranulation: CD107a and b. Method Cell Biol. 75: 497-512
Product options: 16
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
130-103-896

CD107b-PE, human

for 30
tests
(1)
EUR 110,00 
130-103-826

CD107b-PE, human

for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 110,00 
for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 275,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 

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