CD105 antibodies, human

CD105 antibodies, human

Clone: REA794 | Dilution: 1:50
Clone REA794 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin.
Additional information: Clone REA794 displays negligible binding to Fc receptors.

Alternative Names

ENG, END, HHT1, ORW1, Endoglin

Technical specifications

  • Antigen: CD105
  • Clone: REA794
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ENG, END, HHT1, ORW1, Endoglin
  • Entrez Gene ID: 2022
  • Molecular mass of antigen [kDa]: 68
  • Distribution of antigen: bone marrow, endothelial cells, leukemia cells, mesenchymal stem cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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