Anti-TRA-1-81 antibodies, human

Anti-TRA-1-81 antibodies, human

Clone: REA246 | Dilution: 1:11
Clone REA246 recognizes a carbohydrate epitope expressed on podocalyxin, which is a transmembrane sialoglycoprotein. Podocalyxin is a member of the CD34-related family of sialomucins and is recognized as a stem cell and malignancy marker. The expression of TRA-1-81 antigen is stage-specific and is lost upon differentiation of human EC and ES cells, making it a marker of undifferentiated pluripotent ES cells.
Additional information: Clone REA246 displays negligible binding to Fc receptors.

Alternative names

PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin

Technical specifications

  • Antigen: TRA-1-81
  • Clone: REA246
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PODXL, Gp200, PC, PCLP, PCLP-1, Podocalyxin
  • Entrez Gene ID: 5420
  • Molecular mass of antigen [kDa]: 56
  • Distribution of antigen: ES and iPS cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Schopperle, W. M. et al. (2007) The TRA-1-60 and TRA-1-81 human pluripotent stem cell markers are expressed on podocalyxin in embryonal carcinoma. Stem Cells 25(3): 723-730
    2. Abujarour, R. et al. (2013) Optimized surface markers for the prospective isolation of high-quality hiPSCs using flow cytometry selection. Sci. Rep. 3: 1179
Product options: 2
130-101-427

Anti-TRA-1-81-PE, human

for 30
tests
(1)
EUR 110,00 
130-101-410

Anti-TRA-1-81-PE, human

for 100
tests
(1)
EUR 265,00