Anti-TCRγ/δ antibodies, human

Anti-TCRγ/δ antibodies, human

Clone: REA591 | Dilution: 1:11
Clone REA591 recognizes the human TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide–linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules.
Additional information: Clone REA591 displays negligible binding to Fc receptors.

Alternative Names

TCRgd

Technical specifications

  • Antigen: TCRγ/δ
  • Clone: REA591
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCRgd
  • Entrez Gene ID: 6965
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PerCP-Vio700, Biotin
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA591
B1+
11F2++
IMMU510++
Product options: 6

Product information

Size
Order no.
Price

Anti-TCRγ/δ-FITC, human

  • REA591
  • 1:11
  • For research use only
for 30
tests
(1)
130-109-356
EUR 85,00 

Anti-TCRγ/δ-FITC, human

  • REA591
  • 1:11
  • For research use only
for 100
tests
(1)
130-109-278
EUR 248,00 

Anti-TCRγ/δ-PerCP-Vio700, human

  • REA591
  • 1:11
  • For research use only
for 30
tests
(1)
130-109-361
EUR 126,00 

Anti-TCRγ/δ-PerCP-Vio700, human

  • REA591
  • 1:11
  • For research use only
for 100
tests
(1)
130-109-283
EUR 304,00 

Anti-TCRγ/δ-Biotin, human

  • REA591
  • 1:11
  • For research use only
for 30
tests
(1)
130-109-355
EUR 85,00 

Anti-TCRγ/δ-Biotin, human

  • REA591
  • 1:11
  • For research use only
for 100
tests
(1)
130-109-277
EUR 248,00 

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