Anti-TCR Vβ7.2 antibodies, human

Anti-TCR Vβ7.2 antibodies, human

Clone: REA677 | Dilution: 1:11
Clone REA677 recognizes the human Vβ7.2 T cell receptor (TCR Vβ7.2). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. It is suggested that T cells expressing TCRs with Vβ7.2 are protective against a pathogenic immune response in Sjögren's syndrome. TCR Vβ7.2 is expressed on a subset of α/β T cells.
Additional information: Clone REA677 displays negligible binding to Fc receptors.

Alternative names

TCR Vb7.2, TCR Vbeta7.2

Technical specifications

  • Antigen: TCR Vβ7.2
  • Clone: REA677
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vb7.2, TCR Vbeta7.2
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Zhao, T. M. et al. (1994) A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments. J. Exp. Med. 180(4): 1405-1414
    2. Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40(1): 27-36
    3. Manavalan, S. J. et al. (2004) Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome. Arthritis Rheum. 50(1): 187-198
Product options: 10
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 270,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 270,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 230,00 

Related products

2 products available