Anti-p120 Catenin pT310 antibodies, human

Anti-p120 Catenin pT310 antibodies, human

Clone: REA153 | Dilution: 1:11
Clone REA153 recognizes the threonine residue (T310)-phosphorylated form of p120 Catenin, a prototypic member of subfamily of Armadillo-domain (ARM) proteins. p120 ARM domain displays 22% homology to other ARM-domain proteins such as β-catenin and plakoglobin, which are basically cadherin binding proteins, suggesting the involvement of p120 in binding to cadherin. p120 associates with most classical (type I) and nonclassical (type II) cadherins via ARM repeats 1–7 and is localised at the cell junctions, where it constitutes the cadherin complex. Functions of p120 include regulation of stability of cadherins and modulation of activity of rho GTPases in the cytoplasm. Furthermore, lack of p120 Catenin in mouse leads to tumor development, suggesting its further role as tumor supressor. Phosphorylation of p120 Catenin at multiple sites regulates its various functions and it can be phosphorylated by Src and various receptor tyrosine kinases.
Additional information: Clone REA153 displays negligible binding to Fc receptors.

Alternative Names

CTNND1, CAS, CTNND, p120cas, p120ctn, p120, Catenin δ-1

Technical specifications

  • Antigen: p120 Catenin pT310
  • Clone: REA153
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: CTNND1, CAS, CTNND, p120cas, p120ctn, p120, Catenin δ-1
  • Entrez Gene ID: 1500
  • Molecular mass of antigen [kDa]: 108
  • Cross-reactivity: dog, mouse
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, PerCP-Vio700
Product options: 8

Product information

Size
Order no.
Price

Anti-p120 Catenin pT310-PE, human

  • REA153
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-345
EUR 91,00 

Anti-p120 Catenin pT310-PE, human

  • REA153
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-296
EUR 236,00 

Anti-p120 Catenin pT310-APC, human

  • REA153
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-346
EUR 113,00 

Anti-p120 Catenin pT310-APC, human

  • REA153
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-297
EUR 255,00 

Anti-p120 Catenin pT310-PE-Vio770, human

  • REA153
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-347
EUR 113,00 

Anti-p120 Catenin pT310-PE-Vio770, human

  • REA153
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-298
EUR 278,00 

Anti-p120 Catenin pT310-PerCP-Vio700, human

  • REA153
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-348
EUR 113,00 

Anti-p120 Catenin pT310-PerCP-Vio700, human

  • REA153
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-299
EUR 300,00 

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