Anti-p120 Catenin pS879 antibodies, human

Anti-p120 Catenin pS879 antibodies, human

Clone: REA548
Clone REA548 recognizes the S879-phosphorylated form of p120 catenin, a prototypic member of the subfamily of armadillo-domain (ARM) proteins. p120 ARM domain displays 22% homology to other ARM-domain proteins such as β-catenin and plakoglobin, which are basically cadherin binding proteins, suggesting the involvement of p120 in binding to cadherin. p120 associates with most classical (type I) and non-classical (type II) cadherins via ARM repeats 1–7 and is localised at the cell junctions, where it constitutes the cadherin complex. Functions of p120 include regulation of stability of cadherins and modulation of activity of rho GTPases in the cytoplasm. Furthermore, lack of p120 catenin in mouse leads to tumor development, suggesting its further role as tumor supressor. Phosphorylation of p120 catenin at multiple sites regulates its various functions and can be phosphorylated by Src and various receptor tyrosine kinases.
Additional information: Clone REA548 displays negligible binding to Fc receptors.

Alternative Names

CTNND1, CAS, CTNND, p120cas, p120ctn, p120

Technical specifications

  • Antigen: p120 Catenin pS879
  • Clone: REA548
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: CTNND1, CAS, CTNND, p120cas, p120ctn, p120
  • Entrez Gene ID: 1500
  • Molecular mass of antigen [kDa]: 108
  • Distribution of antigen: tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
Product options: 4

Product information

Size
Order no.
Price

Anti-p120 Catenin pS879-PE, human

  • REA548
  • For research use only
for 30
tests
(1)
130-108-868
EUR 110,00 

Anti-p120 Catenin pS879-PE, human

  • REA548
  • For research use only
for 100
tests
(1)
130-108-842
EUR 292,00 

Anti-p120 Catenin pS879-APC, human

  • REA548
  • For research use only
for 30
tests
(1)
130-108-869
EUR 144,00 

Anti-p120 Catenin pS879-APC, human

  • REA548
  • For research use only
for 100
tests
(1)
130-108-843
EUR 317,00 

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