Anti-Oct-2 antibodies, human and mouse

Anti-Oct-2 antibodies, human and mouse

Clone: REA251 | Dilution: 1:11
Clone REA251 recognizes the Octamer-binding protein 2 (Oct-2) antigen, a transcription factor also known as POU domain class 2 transcription factor 2 (POU2F2). Oct-2 is expressed primarily in B lymphocytes and the developing central nervous system. It regulates gene transcription in a number of tissues in addition to activating immunoglobulin gene expression for normal humoral responses to T-dependent and T-independent antigens. Oct-2 binds to conserved sites in immunoglobulin variable gene promoters, several immunoglobulin gene enhancers and to sites in the promoters of other genes whose expression is B cell restricted. Once bound to a promoter, Oct-2 facilitates the assembly of the transcription initiation complex.
Additional information: Clone REA251 displays negligible binding to Fc receptors.

Alternative Names

POU2F2, OTF-2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding transcription factor 2, Octamer-binding protein 2

Technical specifications

  • Antigen: Oct-2
  • Clone: REA251
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: POU2F2, OTF-2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding transcription factor 2, Octamer-binding protein 2
  • Entrez Gene ID: 5452
  • Molecular mass of antigen [kDa]: 51
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
Product options: 4

Product information

Size
Order no.
Price

Anti-Oct-2-PE, human and mouse

  • REA251
  • 1:11
  • For research use only
for 30
tests
(1)
130-103-698
EUR 91,00 

Anti-Oct-2-PE, human and mouse

  • REA251
  • 1:11
  • For research use only
for 100
tests
(1)
130-103-633
EUR 236,00 

Anti-Oct-2-APC, human and mouse

  • REA251
  • 1:11
  • For research use only
for 30
tests
(1)
130-103-699
EUR 113,00 

Anti-Oct-2-APC, human and mouse

  • REA251
  • 1:11
  • For research use only
for 100
tests
(1)
130-103-634
EUR 255,00 

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