Anti-NKp80 antibodies, human

Anti-NKp80 antibodies, human

Clone: 4A4.D10 | Dilution: 1:11
NKp80 is an 80 kDa homodimeric surface molecule and belongs to the family of C-type lectin-like receptors. It is expressed on all human natural killer (NK) cells and a small subset of effector memory CD8
+
T cells. NKp80 stimulates NK cell cytotoxicity and cytokine release and appears to co-operate with other triggering receptors to induce optimal NK cell activation upon interaction with potential target cells. The ligand of NKp80 is AICL (activation-induced C-type lectin), also called CLEC2B.

Alternative Names

KLRF1, CLEC5C

Technical specifications

  • Antigen: NKp80
  • Clone: 4A4.D10
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: KLRF1, CLEC5C
  • Entrez Gene ID: 51348
  • Molecular mass of antigen [kDa]: 27
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin, pure
  • Selected References

    1. Welte, S. et al. (2006) Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Nat. Immunol. 7: 1334-1342
    2. Vitale, M. et al. (2001) Identification of NKp80, a novel triggering molecule expressed by human NK cells. Eur. J. Immunol. 31: 233-242
    3. Kuttruff, S. et al. (2009) NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113: 358-369
Product options: 8

Product information

Size
Order no.
Price

Anti-NKp80-FITC, human

  • 4A4.D10
  • 1:11
  • For research use only
for 100
tests
(1)
130-094-843
EUR 187,00 

Anti-NKp80-PE, human

  • 4A4.D10
  • 1:11
  • For research use only
for 100
tests
(1)
130-094-844
EUR 240,00 

Anti-NKp80-APC, human

  • 4A4.D10
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-608
EUR 113,00 

Anti-NKp80-APC, human

  • 4A4.D10
  • 1:11
  • For research use only
for 100
tests
(1)
130-094-845
EUR 256,00 

Anti-NKp80-PE-Vio770, human

  • 4A4.D10
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-098
EUR 111,00 

Anti-NKp80-PE-Vio770, human

  • 4A4.D10
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-068
EUR 326,00 

Anti-NKp80-Biotin, human

  • 4A4.D10
  • 1:11
  • For research use only
for 100
tests
(1)
130-095-114
EUR 240,00 

Anti-NKp80 pure, human

  • 4A4.D10
  • For research use only
100 µg in 1 mL
130-094-846
EUR 198,00