Anti-NKp80 antibodies, human

Anti-NKp80 antibodies, human

Clone: 4A4.D10 | Dilution: 1:11
NKp80 is an 80 kDa homodimeric surface molecule and belongs to the family of C-type lectin-like receptors. It is expressed on all human natural killer (NK) cells and a small subset of effector memory CD8
+
T cells. NKp80 stimulates NK cell cytotoxicity and cytokine release and appears to co-operate with other triggering receptors to induce optimal NK cell activation upon interaction with potential target cells. The ligand of NKp80 is AICL (activation-induced C-type lectin), also called CLEC2B.

Alternative names

KLRF1, CLEC5C

Technical specifications

  • Antigen: NKp80
  • Clone: 4A4.D10
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: KLRF1, CLEC5C
  • Entrez Gene ID: 51348
  • Molecular mass of antigen [kDa]: 27
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin, pure, FITC
  • Selected references

    1. Welte, S. et al. (2006) Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Nat. Immunol. 7: 1334-1342
    2. Vitale, M. et al. (2001) Identification of NKp80, a novel triggering molecule expressed by human NK cells. Eur. J. Immunol. 31: 233-242
    3. Kuttruff, S. et al. (2009) NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113: 358-369
Product options: 8
for 100
tests
(1)
EUR 220,00 
for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 110,00 
for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 100
tests
(1)
EUR 220,00 
100 µg in 1 mL
EUR 198,00 

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