Anti-Nanog antibodies, human

Anti-Nanog antibodies, human

Clone: REA314 | Dilution: 1:50
Clone REA314 recognizes the human Nanog antigen, a homeobox transcription factor also known as ES cell–associated protein 4. Nanog is thought to be a key factor in maintaining pluripotency. It is expressed in the central portion of the morula, the inner cell mass of the blastocyst, in embryonic stem cells (ESC), and embryonic germ cells (EGC). The expression decreases with ESC differentiation. Nanog is thought to function in concert with other factors such as Oct-4 and SOX2 to establish ESC identity. Inhibition of Nanog expression has led to a reduction in tumorigenicity and such
in vitro
characteristics of stem cells as anchorage independent growth whereas overexpression may increase tumorigenicity.
Additional information: Clone REA314 displays negligible binding to Fc receptors.

Alternative Names

Homeobox protein NANOG, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox transcription factor Nanog (hNanog)

Technical specifications

  • Antigen: Nanog
  • Clone: REA314
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Homeobox protein NANOG, ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Homeobox transcription factor Nanog (hNanog)
  • Entrez Gene ID: 79923
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: ES and iPS cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE

Related products

6 products available | view all
Product options: 2

Product information

Size
Order no.
Price

Anti-Nanog-PE, human

  • REA314
  • 1:50
  • For research use only
for 30
tests
(1)
130-117-526
EUR 112,00 

Anti-Nanog-PE, human

  • REA314
  • 1:50
  • For research use only
for 100
tests
(1)
130-117-377
EUR 78,00