Anti-MSCA-1 antibodies, human

Clone: W8B2 | Dilution: 1:11
Clone W8B2 recognizes the mesenchymal stromal cell antigen-1 (MSCA-1). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271
bright
population in bone marrow. These CD271
bright
CD45
dim
MSCs have a much higher clonogenic capacity compared to the CD271
+
CD45
+
fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential. MSCA-1 expression was not found on placenta-derived MSCs after culture.

Alternative names

ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP

Technical specifications

  • Antigen: MSCA-1
  • Clone: W8B2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
  • Entrez Gene ID: 249
  • Molecular mass of antigen [kDa]: 53
  • Cross-reactivity: dog, pig, sheep, goat, monkey
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin, pure
  • Selected references

    1. Bühring, H. J. et al. (2007) Novel markers for the prospective isolation of human MSC. Ann. N. Y. Acad. Sci. 1106: 262-271
    2. Battula, V. L. et al. (2007) Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation 75: 279-291
    3. Rozemuller, H. et al. (2010) Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies. Stem Cells Dev. 19: 1911-1921
Product options: 6
for 30
tests
(1)
EUR 118,00 
for 100
tests
(1)
EUR 278,00 
for 30
tests
(1)
EUR 118,00 
for 100
tests
(1)
EUR 278,00 
for 100
tests
(1)
EUR 237,00 
100 µg in 1 mL
EUR 203,00 

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