Anti-MICA/MICB antibodies, human

Anti-MICA/MICB antibodies, human

Clone: REA1076 | Dilution: 1:50
Clone REA1076 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA and MICB have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA and MICB are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells.
Additional information: Clone REA1076 displays negligible binding to Fc receptors.

Alternative Names

MICB, PERB11.2, MICA, PERB11.1

Technical specifications

  • Antigen: MICA/MICB
  • Clone: REA1076
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: MICB, PERB11.2, MICA, PERB11.1
  • Entrez Gene ID: 100507436, 4277
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: endothelial cells, epithelial cells, fibroblasts, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected References

    1. Houchins, J. P. et al. (1991) DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173(4): 1017-1020
    2. Bauer, S. et al. (1999) Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285: 727-729
    3. Li, P. et al. (1999) Crystal structure of the MHC class I homolog MIC-A, a γδ T cell ligand. Immunity 10: 577-584

Related products

3 products available
Product options: 14

Product information

Size
Order no.
Price

Anti-MICA/MICB-PE, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-887
EUR 110,00 

Anti-MICA/MICB-PE, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-829
EUR 265,00 

Anti-MICA/MICB-APC, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-888
EUR 110,00 

Anti-MICA/MICB-APC, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-830
EUR 265,00 

Anti-MICA/MICB-PE-Vio615, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-889
EUR 120,00 

Anti-MICA/MICB-PE-Vio615, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-831
EUR 290,00 

Anti-MICA/MICB-PE-Vio770, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-890
EUR 120,00 

Anti-MICA/MICB-PE-Vio770, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-832
EUR 290,00 

Anti-MICA/MICB-PerCP-Vio700, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-892
EUR 120,00 

Anti-MICA/MICB-PerCP-Vio700, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-834
EUR 290,00 

Anti-MICA/MICB-VioBright 515, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-893
EUR 150,00 

Anti-MICA/MICB-VioBright 515, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-835
EUR 360,00 

Anti-MICA/MICB-Biotin, human

  • REA1076
  • 1:50
  • For research use only
for 30
tests
(1)
130-118-894
EUR 90,00 

Anti-MICA/MICB-Biotin, human

  • REA1076
  • 1:50
  • For research use only
for 100
tests
(1)
130-118-836
EUR 220,00