Anti-Ly-6B.2 antibodies, mouse

Anti-Ly-6B.2 antibodies, mouse

Clone: REA115 | Dilution: 1:10
Clone REA115 recognizes Ly-6B.2, a member of the lymphocyte antigen 6 (Ly-6) superfamily and is located on chromosome 15 as the other members of the murine Ly-6 family. The Ly-6 family members are normally GPI-anchored, cysteine-rich cell surface molecules. Expression of Ly-6B.2 antigen has been reported on neutrophils, bone marrow restricted progenitors, monocytes, and is lost during the differentiation of monoytes into tissue resident macrophages or dendritic cell phenotype. High expression of Ly-6B.2 is also associated with inflammatory cell repertoire including monocytes and certain populations of activated macrophages present during infections.
Additional information: Clone REA115 displays negligible binding to Fc receptors.

Alternative names

LY6B

Technical specifications

  • Antigen: Ly-6B.2
  • Clone: REA115
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: LY6B
  • Entrez Gene ID: 110453
  • Distribution of antigen: neutrophils, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Rosas, M. et al. (2010) The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J. Leukoc. Biol. 88: 169-180
    2. Hirsch, S. et al. (1983) Polymorphic expression of a neutrophil differentiation antigen revealed by monoclonal antibody 7/4. Immunogenetics 18(3): 229-239
Product options: 13
9 µg in 300 µL (1)
EUR 20,00 
30 µg in 1 mL (1)
EUR 40,00 
9 µg in 300 µL (1)
EUR 27,00 
30 µg in 1 mL (1)
EUR 80,00 
9 µg in 300 µL (1)
EUR 44,00 
30 µg in 1 mL (1)
EUR 80,00 
9 µg in 300 µL (1)
EUR 52,00 
30 µg in 1 mL (1)
EUR 100,00 
9 µg in 300 µL (1)
EUR 56,00 
30 µg in 1 mL (1)
EUR 100,00 
30 µg in 1 mL (1)
EUR 100,00 
9 µg in 300 µL (1)
EUR 15,00 
30 µg in 1 mL (1)
EUR 40,00 

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