Anti-IL-6 antibodies – functional grade, mouse

Anti-IL-6 antibodies – functional grade, mouse

Clone: MP5-20F3
Interleukin 6 (IL-6), originally identified as a B cell differentiation factor, is a multifunctional cytokine, which regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions. It induces the terminal maturation of activated B cells into antibody-secreting plasma cells and acts in synergy with IL-3 to support the proliferation of hematopoietic stem cells. IL-6 is produced by many cell types, such as monocytes, fibroblasts, endothelial cells, eosinophils, and T cells. Disturbed IL-6 production has been associated with pathological processes, including inflammatory autoimmune diseases and cancer.

Applications

This pure – functional grade antibody is suited for functional assays, for example, neutralization of cytokine activity.

Technical specifications

  • Antigen: IL-6
  • Clone: MP5-20F3
  • Isotype: rat IgG1
  • Entrez Gene ID: 16193
  • Molecular mass of antigen [kDa]: 22
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

Anti-IL-6 pure - functional grade, mouse

  • MP5-20F3
  • For research use only
500 µg in 0.5 mL
130-096-130
EUR 311,00 

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