Anti-IL-2 antibodies, human

Anti-IL-2 antibodies, human

Clone: REA689 | Dilution: 1:50
Clone REA689 recognizes the human interleukin-2 (IL-2), a cytokine which is produced by cells that are involved in inflammatory immune responses. IL-2 is rapidly secreted by naive CD4
+
T cells and by central memory T cells upon activation. It promotes growth and differentiation of T cells and has pleiotropic effects on many other leukocytes.
Additional information: Clone REA689 displays negligible binding to Fc receptors.

Alternative Names

T cell growth factor, TCGF

Technical specifications

  • Antigen: IL-2
  • Clone: REA689
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: T cell growth factor, TCGF
  • Entrez Gene ID: 3558
  • Molecular mass of antigen [kDa]: 15
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770

REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 

Other clonesOverlap in epitope recognition with REA689
N7.48A-
REA105+
MQ1-17H12++
  • Selected References

    1. Fujita, T. et al. (1983) Structure of the human interleukin 2 gene. Proc. Natl. Acad. Sci. U.S.A. 80(24): 7437-7441
    2. Gaffen, S. L. et al. (2004) Overview of interleukin-2 function, production and clinical applications. Cytokine 28(3): 109-123
    3. Liao, W. et al. (2011) IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation. Curr. Opin. Immunol. 23(5): 598-604
Product options: 12

Product information

Size
Order no.
Price

Anti-IL-2-FITC, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-488
EUR 90,00 

Anti-IL-2-FITC, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-302
EUR 220,00 

Anti-IL-2-PE, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-489
EUR 110,00 

Anti-IL-2-PE, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-303
EUR 265,00 

Anti-IL-2-APC, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-490
EUR 110,00 

Anti-IL-2-APC, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-304
EUR 265,00 

Anti-IL-2-PE-Vio615, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-493
EUR 120,00 

Anti-IL-2-PE-Vio615, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-307
EUR 290,00 

Anti-IL-2-PE-Vio770, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-491
EUR 120,00 

Anti-IL-2-PE-Vio770, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-305
EUR 290,00 

Anti-IL-2-APC-Vio770, human

  • REA689
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-492
EUR 120,00 

Anti-IL-2-APC-Vio770, human

  • REA689
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-306
EUR 290,00