Anti-IL-10 antibodies, mouse

Anti-IL-10 antibodies, mouse

Clone: REA1008 | Dilution: 1:50
Clone REA1008 recognizes the interleukin-10 (IL-10) cytokine, which is predominantly secreted by CD4
+
T cells and antigen-presenting cells, such as monocytes/macrophages and dendritic cells. IL-10 has important suppressive functions on immune responses and is believed to be involved in the maintenance of tolerance. IL-10 blocks activation of cytokine synthesis by Tʜ1 cells, activated monocytes, and NK cells. It can stimulate immunoglobulin production by B cells.
Additional information: Clone REA1008 displays negligible binding to Fc receptors.

Alternative names

IL10, CSIF, Interleukin-10

Technical specifications

  • Antigen: IL-10
  • Clone: REA1008
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: IL10, CSIF, Interleukin-10
  • Entrez Gene ID: 16153
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: dendritic cells, macrophages, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, Vio515, Vio667
  • Selected references

    1. Ajuebor, M. N. et al. (1999) Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation. Biochem. Biophys. Res. Commun. 255(2): 279-282
    2. Assaman, C. et al. (1999) An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190(7): 995-1004
Product options: 8
130-116-965

Anti-IL-10-FITC, mouse

30 µg in 200 µL (1)
EUR 40,00 
130-116-845

Anti-IL-10-FITC, mouse

150 µg in 1 mL (1)
EUR 120,00 
130-116-966

Anti-IL-10-PE, mouse

30 µg in 200 µL (1)
EUR 80,00 
130-116-846

Anti-IL-10-PE, mouse

150 µg in 1 mL (1)
EUR 230,00 
130-116-968

Anti-IL-10-Vio515, mouse

30 µg in 200 µL (1)
EUR 95,00 
130-116-848

Anti-IL-10-Vio515, mouse

150 µg in 1 mL (1)
EUR 275,00 
130-116-969

Anti-IL-10-Vio667, mouse

30 µg in 200 µL (1)
EUR 95,00 
130-116-849

Anti-IL-10-Vio667, mouse

150 µg in 1 mL (1)
EUR 275,00