Anti-HLA Class I B8 antibodies, human

Anti-HLA Class I B8 antibodies, human

Clone: REA145 | Dilution: 1:11
Clone REA145 recognizes HLA B8, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells.
Additional information: Clone REA145 displays negligible binding to Fc receptors.

Alternative Names

HLA-B, AS, SPDA1

Technical specifications

  • Antigen: HLA Class I B8
  • Clone: REA145
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLA-B, AS, SPDA1
  • Entrez Gene ID: 3106
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, granulocytes, T cells, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin

Related products

3 products available
Product options: 10

Product information

Size
Order no.
Price

Anti-HLA Class I B8-APC, human

  • REA145
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-595
EUR 113,00 

Anti-HLA Class I B8-APC, human

  • REA145
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-592
EUR 255,00 

Anti-HLA Class I B8-PE-Vio770, human

  • REA145
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-609
EUR 113,00 

Anti-HLA Class I B8-PE-Vio770, human

  • REA145
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-608
EUR 278,00 

Anti-HLA Class I B8-APC-Vio770, human

  • REA145
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-590
EUR 101,00 

Anti-HLA Class I B8-APC-Vio770, human

  • REA145
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-583
EUR 278,00 

Anti-HLA Class I B8-PerCP-Vio700, human

  • REA145
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-600
EUR 101,00 

Anti-HLA Class I B8-PerCP-Vio700, human

  • REA145
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-606
EUR 300,00 

Anti-HLA Class I B8-Biotin, human

  • REA145
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-589
EUR 74,00 

Anti-HLA Class I B8-Biotin, human

  • REA145
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-588
EUR 236,00