Anti-Granzyme A antibodies, human

Anti-Granzyme A antibodies, human

Clone: REA162 | Dilution: 1:10
Clone REA162 recognizes granzyme A, a member of serine protease family expressed exclusively by cytotoxic T lymphocytes and natural killer (NK) cells. Granzyme A is a homodimeric protease and is one of the five granzymes expressed by humans. Also known as granule enzymes, granzymes comprise majority of the mass of cytolytic granules in cytotoxic T lymphocytes (CTLs) and NK cells. NK cells and γδ T cells express granzymes constitutively, whereas expression in T lymphocytes is stimulation dependent. Main function attributed to granzymes is to indue apoptotic death of infected and transformed cells. Granzymes other than granzyme B, exert relatively weaker apoptotic activity. Additional reported functions of granzyme A include, to facilitate the migration of T and NK cells and induction of cytokine secretion.
Additional information: Clone REA162 displays negligible binding to Fc receptors.

Alternative Names

GZMA, CTLA-3, HFSP, Granzyme 1

Technical specifications

  • Antigen: Granzyme A
  • Clone: REA162
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: GZMA, CTLA-3, HFSP, Granzyme 1
  • Entrez Gene ID: 3001
  • Molecular mass of antigen [kDa]: 26
  • Distribution of antigen: T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
Product options: 4

Product information

Size
Order no.
Price

Anti-Granzyme A-PE, human

  • REA162
  • 1:10
  • For research use only
for 30
tests
(1)
130-099-797
EUR 91,00 

Anti-Granzyme A-PE, human

  • REA162
  • 1:10
  • For research use only
for 100
tests
(1)
130-099-796
EUR 236,00 

Anti-Granzyme A-APC, human

  • REA162
  • 1:10
  • For research use only
for 30
tests
(1)
130-099-789
EUR 113,00 

Anti-Granzyme A-APC, human

  • REA162
  • 1:10
  • For research use only
for 100
tests
(1)
130-099-780
EUR 255,00 

Related products

4 products available