Anti-GPR56 antibodies, human

Anti-GPR56 antibodies, human

Clone: REA467 | Dilution: 1:11
Clone REA467 recognizes the human G-protein coupled receptor 56 (GPR56) antigen, a multi-pass membrane protein, which is also known as TM7XN1. GPR56 is a member of the adhesion-GPCR family of receptors, which are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-autoproteolysis inducing (GAIN) domain. It is expressed in a wide range of tissues, such as brain, thyroid gland, and heart. GPR56 has been shown to have numerous roles in cell guidance/adhesion as exemplified by its roles in tumor inhibition and neuron development. It is a receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. More recently it has been shown to be a marker for cytotoxic T cells and a subgroup of natural killer cells. In melanocytic cells GPR56 gene expression may be regulated by MITF.
Additional information: Clone REA467 displays negligible binding to Fc receptors.

Alternative Names

ADGRG1, BFPP, BPPR, TM7LN4, TM7XN1

Technical specifications

  • Antigen: GPR56
  • Clone: REA467
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ADGRG1, BFPP, BPPR, TM7LN4, TM7XN1
  • Entrez Gene ID: 9289
  • Molecular mass of antigen [kDa]: 75
  • Distribution of antigen: brain, heart, T cells, NK cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

Anti-GPR56-VioBright FITC, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-979
EUR 154,00 

Anti-GPR56-VioBright FITC, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-915
EUR 308,00 

Anti-GPR56-PE, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-975
EUR 112,00 

Anti-GPR56-PE, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-911
EUR 296,00 

Anti-GPR56-APC, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-976
EUR 146,00 

Anti-GPR56-APC, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-912
EUR 322,00 

Anti-GPR56-PE-Vio770, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-977
EUR 146,00 

Anti-GPR56-PE-Vio770, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-913
EUR 322,00 

Anti-GPR56-APC-Vio770, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-978
EUR 129,00 

Anti-GPR56-APC-Vio770, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-914
EUR 308,00 

Anti-GPR56-Biotin, human

  • REA467
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-974
EUR 86,00 

Anti-GPR56-Biotin, human

  • REA467
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-910
EUR 252,00 

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