Anti-GATA3 antibodies, human and mouse

Anti-GATA3 antibodies, human and mouse

Clone: REA174
Clone REA174 recognizes GATA3, a member of the GATA family of transcription factors. Like other members of the family, GATA3 contain zinc finger motifs involved in recognizing the canonical GATA DNA sequence. GATA3 has two trans-activating domains and two zinc finger domains, each followed by a conserved basic region. Expression of GATA3 is found in developing and mature T cells, natural killer (NK) cells, subset of NKT cells, and endothelial cells. Primary function attributed to GATA3 is to regulate the T helper 2 (Tʜ2) cell differentiation. However, role of GATA3 is also recognized in early T cell commitment and CD4
+
T cell development .
Additional information: Clone REA174 displays negligible binding to Fc receptors.      

Alternative Names

HDR, HDRS, jal

Technical specifications

  • Antigen: GATA3
  • Clone: REA174
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: HDR, HDRS, jal
  • Entrez Gene ID: 2625
  • Molecular mass of antigen [kDa]: 48
  • Distribution of antigen: T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

Anti-GATA3 pure, human and mouse

  • REA174
  • For research use only
100 µg in 100 µL
130-108-061
EUR 184,00