Anti-FcεRIα antibodies – functional grade, human

Anti-FcεRIα antibodies – functional grade, human

Clone: CRA1
Clone CRA1 detects the alpha subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one alpha-, one beta-, and two disulfid-linked gamma subunits, of which the alpha subunit binds IgE. FcεRIα is expressed on mast and basophilic cells and is upregulated in the presence of IgE, and is found on a subset of blood dendritic cells. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. Clone CRA1 does not inhibit binding of IgE, it induces mast cell activation, followed by histamin release.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

FCER1A, Fce1a, FcERI

Technical specifications

  • Antigen: FcεRIα
  • Clone: CRA1
  • Isotype: mouse IgG2b
  • Alternative names of antigen: FCER1A, Fce1a, FcERI
  • Entrez Gene ID: 2205
  • Molecular mass of antigen [kDa]: 27
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

Anti-FcεRIα pure - functional grade, human

  • CRA1
  • For research use only
100 µg in 1 mL
130-096-004
EUR 165,00 

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