Anti-DLL4 antibodies, mouse

Anti-DLL4 antibodies, mouse

Clone: HMD4-1 | Dilution: 1:10
DLL4 is one of the six identified Notch ligands in vertebrates. Being a canonical Notch ligand, extracellular domain of DLL4 contains N-terminal domain, Delta/Serrate/LAG-2 (DSL) domain and tandemly arranged multiple EGF like repeats. Binding of canonical ligands such as DLL4 induces cleavage and release of Notch intracellular domain (NICD), followed by its translocation in the nucleus where it interacts with transcription factors involved in induction of expression of Notch target genes. A ligand for Notch1, DLL4 is the first Notch ligand to be expressed during mouse development. DLL4 plays an important role in developmental angiogenesis. In mice, lack of a single DLL4 allele leads to early embryonic lethality characterized by severe defects in arterial differentiation and vascular remodeling.

Alternative Names

Delta4

Technical specifications

  • Antigen: DLL4
  • Clone: HMD4-1
  • Isotype: hamster IgG
  • Alternative names of antigen: Delta4
  • Entrez Gene ID: 54485
  • Molecular mass of antigen [kDa]: 72
  • Distribution of antigen: endothelial cells, heart
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 6

Product information

Size
Order no.
Price

Anti-DLL4-PE, mouse

  • HMD4-1
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-947
EUR 27,00 

Anti-DLL4-PE, mouse

  • HMD4-1
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-449
EUR 54,00 

Anti-DLL4-APC, mouse

  • HMD4-1
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-946
EUR 44,00 

Anti-DLL4-APC, mouse

  • HMD4-1
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-423
EUR 86,00 

Anti-DLL4-Biotin, mouse

  • HMD4-1
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-031
EUR 15,00 

Anti-DLL4-Biotin, mouse

  • HMD4-1
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-897
EUR 32,00