Anti-Claudin-3 antibodies, human

Anti-Claudin-3 antibodies, human

Clone: REA751 | Dilution: 1:50
Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for
Clostridium perfringens
enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis.
Additional information: Clone REA751 displays negligible binding to Fc receptors.

Alternative names

CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2

Technical specifications

  • Antigen: Claudin-3
  • Clone: REA751
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2
  • Distribution of antigen: epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Morita, K. et al. (1999) Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. U.S.A. 96(2): 511-516
    2. Furuse, M. et al. (1999) Manner of interaction of heterogeneous claudin species within and between tight junction strands. J. Cell Biol. 147(4): 891-903
    3. Coyne, C. B. et al. (2003) Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell Mol. Physiol. 285(5): 1166-1178
Product options: 6
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 270,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 270,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 230,00 

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