Anti-CCL19 (MIP-3β) antibodies, human

Anti-CCL19 (MIP-3β) antibodies, human

Clone: REA597 | Dilution: 1:10
Clone REA597 recognizes the human CCL19 antigen, which is also known as MIP-3β or ELC (EBI1-ligand chemokine). In general, cytokines are secreted proteins involved in immunoregulatory and inflammatory processes. CCL19 induces its effects on its target cells by binding to the chemokine receptor CCR7. The expression of CCL19 is strongly regulated by the anti-inflammatory cytokine IL-10 and is restricted to lymph nodes, thymus, appendix, and spleen.
Additional information: Clone REA597 displays negligible binding to Fc receptors.

Alternative names

C-C motif chemokine 19, MIP-3-beta, ELC, MIP-3-β

Technical specifications

  • Antigen: CCL19 (MIP-3β)
  • Clone: REA597
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: C-C motif chemokine 19, MIP-3-beta, ELC, MIP-3-β
  • Entrez Gene ID: 6363
  • Molecular mass of antigen [kDa]: 9
  • Distribution of antigen: lymph node, spleen, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Rossi, D. L. et al. (1997) Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta. J. Immunol. 158(3): 1033-1036
    2. Yoshida, R. et al. (1997) Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J. Biol. Chem. 272(21): 13803-13809
    3. Robbiani, D. F. et al. (2000) The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. Cell 103(5): 757-768
Product options: 6
130-109-643

Anti-CCL19 (MIP-3β)-FITC, human

for 30
tests
(1)
EUR 90,00 
130-109-584

Anti-CCL19 (MIP-3β)-FITC, human

for 100
tests
(1)
EUR 220,00 
130-109-644

Anti-CCL19 (MIP-3β)-PE, human

for 30
tests
(1)
EUR 110,00 
130-109-585

Anti-CCL19 (MIP-3β)-PE, human

for 100
tests
(1)
EUR 265,00 
130-109-645

Anti-CCL19 (MIP-3β)-APC, human

for 30
tests
(1)
EUR 110,00 
130-109-586

Anti-CCL19 (MIP-3β)-APC, human

for 100
tests
(1)
EUR 265,00 

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