Anti-Bcl-2 antibodies, human

Anti-Bcl-2 antibodies, human

Clone: REA872 | Dilution: 1:50
Clone REA872 recognizes the human Bcl-2 antigen, which is an intracellular single-pass membrane protein found primarily in the mitochondrion outer membrane, the nucleus membrane, and the endoplasmic reticulum membrane. Bcl-2 is a member of the Bcl-2 family of regulator proteins and it forms homodimers or heterodimers with other Bcl-2 family members. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability and it appears to function in a feedback loop system with caspases. Caspase activity is either inhibited by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor.
Additional information: Clone REA872 displays negligible binding to Fc receptors.

Alternative Names

BCL2

Technical specifications

  • Antigen: Bcl-2
  • Clone: REA872
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: BCL2
  • Entrez Gene ID: 596
  • Molecular mass of antigen [kDa]: 26
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
Product options: 6

Product information

Size
Order no.
Price

Anti-Bcl-2-FITC, human

  • REA872
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-337
EUR 86,00 

Anti-Bcl-2-FITC, human

  • REA872
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-230
EUR 252,00 

Anti-Bcl-2-PE, human

  • REA872
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-338
EUR 112,00 

Anti-Bcl-2-PE, human

  • REA872
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-231
EUR 296,00 

Anti-Bcl-2-APC, human

  • REA872
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-339
EUR 146,00 

Anti-Bcl-2-APC, human

  • REA872
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-232
EUR 322,00 

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