CD62L MicroBeads, mouse

CD62L MicroBeads, mouse

Mouse CD62L (L-selectin) MicroBeads were developed for the positive selection or depletion of T cell subsets from lymph nodes or spleen.

Background information

CD62L is highly expressed on naive T cells and down-regulated upon activation. It is also expressed on a small subset of memory T cells, the central memory T cells, which can be distinguished from naive T cells by their high expression of CD44. Furthermore, CD62L is expressed on most thymocytes, naive cytotoxic T cells, B cells, dendritic cells, macrophages, NK cells, neutrophils, and eosinophils.
For isolation of CD4
+
CD62L
+
naive T cells, the CD4
+
CD62L
+
T Cell Isolation Kit II is available.

Downstream applications

Naive T cells isolated following a MultiSort strategy were used for studies on cytokine expression,
1,2
receptor signaling,
3
and T cell activation by different antigen-presenting cells.
4

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.
Product options: 1

Product information

Size
Order no.
Price

CD62L MicroBeads, mouse

  • For research use only
for 2×
10
9
total cells
130-049-701
EUR 646,00 

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