CD57 MicroBeads, human

CD57 MicroBeads, human

CD57 MicroBeads were developed for the positive selection or depletion of CD57
+
cells from human PBMCs, body fluids, or single-cell suspensions from tissue (e.g. lymphoid tissues).

Background information

The CD57 antigen, also known as HNK-1 or Leu-7, is an oligosaccharide antigenic moiety bound to surface proteins of certain cell types. CD57 is present on 15–20% of PBMCs, including subsets of NK cells and T cells and some neural cell types.
1,2
CD57 has been shown to be expressed on late-stage CD8
+
effector cells
3
and terminally differentiated NK cells.
The frequency of CD57
+
T lymphocytes is raised in a variety of diseases, for example, in rheumatoid arthritis
4
. Its expression is also increased on proliferation-incompentent or chronically activated CD8
+
T cells in persistent viral infections, such as HIV.
5

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, CS, D, or autoMACS Columns.
Product options: 1

Product information

Size
Order no.
Price

CD57 MicroBeads, human

  • For research use only
for 1×
10
9
total cells
130-092-073
EUR 561,00