CD133 MicroBead Kit, human

CD133 MicroBead Kit, human

The CD133 MicroBead Kit allows basic isolation or depletion of CD133
+
cells from various sources.
Note:
Optimized isolation kits with improved performance are available for the following tissues:
  • For hematopoietic or endothelial progenitor cells, choose the CD133 MicroBead Kit – Hematopoietic Tissue
  • For cancer or tissue stem cells the CD133 MicroBead Kit – Tumor Tissue is recommended

Background information

CD133, formerly known as AC133, recognizes epitope 1 of the CD133 antigen.
2,3
It is a marker that is frequently found on multipotent progenitor cells, including immature hematopoietic stem and progenitor cells. In the hematopoietic system, CD133 is expressed on a small portion of CD34
cells
4
as well as on a subset of CD34
bright
stem and progenitor cells in human fetal liver, bone marrow, cord blood, and peripheral blood
5
. CD133 has also been found to be expressed on circulating endothelial progenitor cells,
6,7
fetal neural stem cells,
8,9
other tissue-specific stem cells, such as renal
10
, prostate
11
, and corneal
12
stem cells, cancer stem cells from tumor tissues, as well as ES and iPS cell-derived cells.
There is a growing interest in CD133-expressing stem cells from normal blood or bone marrow in regenerative medicine, for example, in the field of cardiovascular
13-17
, liver, or peripheral artery diseases
18-20
.
The CD133 MicroBeads included in the kit recognize epitope CD133/1. For quality control staining of isolated CD133
+
cells, the use of CD133/2 (293C3)-PE or -APC is recommended.

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, CS, D, or autoMACS Columns.

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Product information

Size
Order no.
Price

CD133 MicroBead Kit, human - lyophilized

  • For research use only
for 2×
10
9
total cells
130-097-049
EUR 650,00