CytoStim, non-human primate

CytoStim, non-human primate

CytoStim has been developed for rapid and efficient restimulation of non-human primate effector/memory T cells.

Background information

CytoStim causes activation of T cells by binding to the T cell receptor (TCR) and cross-linking it to a major histocompatibility complex molecule of an antigen–presenting cell. CytoStim is an antibody–based reagent that acts similarly to a superantigen but independently of certain Vβ domains of the TCR. Upon incubation with CytoStim, CD4
+
and CD8
+
cells start to secrete effector cytokines or up-regulate activation markers on their cell surface within a few hours. CytoStim is suitable for rapid stimulation of CD4
+
and CD8
+
T cells in fresh PBMCs, whole blood, or other leukocyte-containing single-cell suspensions from tissues. It can be used instead of SEB as a positive control in antigen-specific T cell stimulation assays or intracellular cytokine staining experiments to detect cytokine or activation marker expression.
Product options: 2

Product information

Size
Order no.
Price

CytoStim, non-human primate

  • For research use only
for 1×
10
8
total cells
130-094-447
EUR 136,00 

CytoStim, non-human primate

  • For research use only
for 5×
10
8
total cells
130-094-442
EUR 415,00