StemMACS™ RepSox

StemMACS™ RepSox

StemMACS™ RepSox is a small molecule inhibitor of the TGFβ type I receptor ALK5.

Background information

StemMACS™ RepSox is an inhibitor of the TGF-β type I receptor ALK5. RepSox prevents autophosphorylation of the ALK5 receptor
1
. It has been shown to promote reprogramming efficiency by replacing Sox2 and inducing Nanog.
  • Selected References

    1. Gellibert, F. et al. (2004) Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J. Med. Chem. 47: 4494-4506
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Product information

Size
Order no.
Price

StemMACS RepSox

  • For research use only
10 mg
130-117-340
EUR 174,00