Mouse RANTES

Mouse RANTES

RANTES stands for regulated upon activation, normal T-cell expressed and secreted, also termed C-C motif chemokine 5 (CCL5). Mouse RANTES is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Mouse RANTES can be used for a variety of applications, including:
  • Investigation of inflammatory processes.
  • Chemotactic assays.

Alternative Names

CCL5

Background information

RANTES is a chemoattractant for monocytes, memory T cells, basophils, and eosinophils. RANTES is secreted by many cell types at inflammatory sites and acts through the binding to CCR1, CCR3, and CCR5 receptors. It causes the release of histamine from basophils and activates eosinophils. Furthermore, it can induce the proliferation and activation of killer cells known as CC-chemokine-activated killer (CHAK). RANTES-deficient mice show an impaired T cell function.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Biological activity

  • Chemotaxis of human lymphocytes
Product options: 1

Product information

Size
Order no.
Price

Mouse RANTES, research grade

  • E. coli
  • For research use only
20 µg
130-094-077
EUR 190,00