Human IL-27

Human IL-27

IL-27 stands for interleukin 27. Human IL-27 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human Interleukin 27 can be used for a variety of applications, including:
  • Research on autoimmune diseases.
  • Cancer Research.
  • Study of dendritic cell development.

Background information

Interleukin 27 (IL-27) is a heterodimeric protein consisting of EBI-3 (IL-27B) and IL-27p28 (IL-27A). IL-27 forms together with IL-12, IL-23, and IL-35 a family of heterodimeric proteins. Produced as an early product of antigen-presenting cells (APC), IL-27 plays a role in the adaptive immune response by promoting the clonal expansion of naive CD4
+
T-cells. It has also been shown that IL-27 has the ability to induce CD8
+
mediated tumor-specific protective immunity.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Biological activity

  • Proliferation of human TF-1 cells
  • research grade: ≥ 2×
    10
    3
    U/mg
Product options: 2

Product information

Size
Order no.
Price

Human IL-27, research grade

  • HEK293 cells
  • For research use only
2 µg
130-108-960
EUR 55,00 

Human IL-27, research grade

  • HEK293 cells
  • For research use only
10 µg
130-108-961
EUR 185,00