Human IL-24

Human IL-24

IL-24 stands for interleukin 24. Human IL-24 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human IL-24 can be used for a variety of applications including:
  • In vitro studies of tumor cell immunosuppression.
  • Investigation on angiogenesis and cell proliferation.
  • Study of cytokine-receptor signaling and JAK1/STAT3 phosphorylation cascade.

Background information

Interleukin 24 (IL-24) is a pleiotropic immune cytokine belonging to the IL-10 family, which includes several members (IL-19, IL-20, IL-22, IL-24, IL-26). IL-24 is secreted by several myeloid and lymphoid cells and also by tumor cells, and acts on immune cells as well as on non-hematopoietic tissues. It is specific for two different heterodimeric receptors, IL-20R1/IL-20R2 and IL-22R1/IL-20R2, and can control cell differentiation and apoptosis, as well as tumor growth, acting on angiogenesis and cell proliferation. IL-24 plays an important role in tumor immune surveillance, but also in skin related diseases and wound healing.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
Product options: 2

Product information

Size
Order no.
Price

Human IL-24, research grade

  • CHO cells
  • For research use only
5 µg
130-105-779
EUR 55,00 

Human IL-24, research grade

  • CHO cells
  • For research use only
20 µg
130-105-777
EUR 190,00