Human EGF

Human EGF

EGF stands for epidermal growth factor. Human EGF is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human EGF can be used for a variety of applications, including:
  • Proliferation and differentiation of a wide variety of cell types deriving from ectoderm and mesoderm.

Background information

Epidermal growth factor (EGF) is the prototype of the large family of EGF-like proteins with a common structural motif comprising three intramolecular disulfide bonds. EGF is produced by various cell types like mammary gland cells, gut epithelial cells, and cells in the nervous system and the kidney. Production of EGF is induced by testosterone and inhibited by estrogens. EGF stimulates the proliferation and differentiation of mesenchymal cells, acts as a mitogen for fibroblasts, epithelial and endothelial cells, and promotes colony formation of epidermal cells.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Biological activity

  • Proliferation of 3T3 cells
  • premium grade: ≥ 0.8×
    10
    6
    IU/mg
    (typical activity: ≥ 2×
    10
    6
    IU/mg
    )
  • research grade: ≥ 0.5×
    10
    6
    IU/mg
Product options: 4

Product information

Size
Order no.
Price

Human EGF, research grade

  • E. coli
  • For research use only
100 µg
130-093-825
EUR 55,00 

Human EGF, premium grade

  • E. coli
  • For research use only
100 µg
130-097-749
EUR 70,00 

Human EGF, premium grade

  • E. coli
  • For research use only
500 µg
130-097-750
EUR 190,00 

Human EGF, premium grade

  • E. coli
  • For research use only
1000 µg
130-097-751
EUR 265,00 

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